Keep an eye on Intently (3)pentobarbital will reduce the extent or impact of diazepam intranasal by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check. Solid or reasonable CYP3A4 inducers may perhaps increase rate of diazepam elimination; thus, efficacy of diazepam may be reduced.
Pentobarbital belongs to the barbiturate class of medicines and mostly performs primarily on the central anxious procedure (CNS).
pentobarbital will lessen the extent or effect of erlotinib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.
pentobarbital will reduce the extent or outcome of phenytoin by affecting hepatic enzyme CYP2C9/ten metabolism. Use Warning/Monitor.
pentobarbital will lessen the level or result of celecoxib by influencing hepatic enzyme CYP2C9/10 metabolism. Minimal/Significance Unfamiliar.
Stay away from; coadministration with CYP3A inducers may bring about lowered plasma concentrations of elvitegravir and/or maybe a concomitantly administered protease inhibitor and bring on loss of therapeutic influence and to feasible resistance
pentobarbital will lessen the extent or influence of capivasertib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Prevent or Use Alternate Drug. Solid or reasonable CYP3A inducers lower capivasertib exposure, which may reduce efficacy.
pentobarbital will decrease the level or effect of paclitaxel by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Importance Not more info known.
benzhydrocodone/acetaminophen and pentobarbital each increase sedation. Stay clear of or Use Alternate Drug. Restrict use to sufferers for whom option treatment selections are insufficient
pentobarbital will reduce the level or effect of rabeprazole by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Mysterious.
pentobarbital will decrease the extent or outcome of lonafarnib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Lonafarnib is really a delicate CYP3A4 substrate. Coadministration with robust or reasonable CYP3A4 inducers is contraindicated.
pentobarbital will lessen the extent or impact of ethinylestradiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. The efficacy of hormonal contraceptives may very well be decreased. Usage of a nonhormonal contraceptive is usually recommended.
Monitor Closely (1)pentobarbital will reduce the extent or impact of gefitinib by impacting hepatic/intestinal enzyme CYP3A4 metabolism.
Contraindicated (one)pentobarbital will lessen the level or outcome of lumacaftor/ivacaftor by impacting hepatic/intestinal enzyme CYP3A4 metabolism.